Serious primary post-partum hemorrhage, arterial embolization and future fertility: a retrospective study of 46 cases.

C. Chauleur 1 C. Fanget G. Tourne R. Levy 2 C. Larchez P. Seffert
1 GRT (EA 3065) - Groupe de recherche sur la thrombose
2 LBP - Laboratoire de Biophotonique et Pharmacologie - UMR 7213
Abstract : BACKGROUND: The guidelines advise arterial embolization in case of post-partum hemorrhage. We evaluated its feasibility and the subsequent fertility. METHODS: A retrospective study has been conducted in our center for the past 10 years (1996-2005). Fifty-two patients experiencing a primary post-partum hemorrhage who were resistant to medical treatment underwent uterine artery embolization and/or hysterectomy. In case of arterial embolization, a follow-up of all the patients was realized, focusing on the preservation of fertility. RESULTS: Six (11.5%) patients underwent hysterectomy straightaway and 46 (88.5%) arterial embolization in the first instance including 35 arterial embolizations after Cesarean section. Embolization was successful among 41 patients (89.1%) and hysterectomy was performed on the 5 (10.9%) others. Overall, 11/24 398 women suffered from a definitive loss of fertility after post-partum hemorrhage. Fertility was studied at least 1 year after the delivery. All patients had a return of normal menses. Sixteen of 41 women (39%) wanted another child and 100% succeeded. Nineteen pregnancies, including two twin pregnancy and one early spontaneous abortion were observed. CONCLUSIONS: Embolization is a safe and effective non-surgical method to resolve post-partum hemorrhage and should be regarded as gold standard in a hemodynamically stable patient. Furthermore, subsequent fertility is not impaired by the procedure.
Document type :
Journal articles
Complete list of metadatas
https://hal-ujm.archives-ouvertes.fr/ujm-00440351
Contributor : Patrick Mismetti <>
Submitted on : Thursday, December 10, 2009 - 2:29:16 PM
Last modification on : Friday, October 19, 2018 - 11:46:40 AM

Links full text

openaccess

Identifiers

Collections

UNIV-ST-ETIENNE | SITE-ALSACE

Citation

C. Chauleur, C. Fanget, G. Tourne, R. Levy, C. Larchez, et al.. Serious primary post-partum hemorrhage, arterial embolization and future fertility: a retrospective study of 46 cases.. Human Reproduction, Oxford University Press (OUP), 2008, 23 (7), pp.1553-9. ⟨10.1093/humrep/den122⟩. ⟨ujm-00440351⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

87

Contact

support.ccsd.cnrs.fr
hal.support@ccsd.cnrs.fr
Logo CCSD